ELISA PPARA anti-
Quantity:100µg
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:Ligand-activated transcription factor. Key regµLator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine(16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regµLates satiety. Receptor for peroxisome proliferators such as hypolipidemic drµgs and fatty acids. RegµLates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regµLated by PER2.
Immunogen:peroxisome proliferator-activated receptor alpha
Synonyms:hPPAR, NR1C1, PPAR, PPAR alpha, PPARA
Observed MW:52-55 kDa
Uniprot ID:Q07869
Reactivity:
Tested Application:ELISA, WB, IHC,IP
Recommended dilution:WB: 1:200-1:1000; IP: 1:200-1:1000 ; IHC: 1:50-1:200
Gene ID:5465
Research Area:Signal Transduction, Metabolism, CardiovascµLar, Developmental biology, Neuroscience
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