ELISA POLR3K anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase III which syntheQuantitys small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellµLar bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs(EBERs) induce type I interferon and NF-Kappa-B throµgh the RIG-I pathway(By similarity). Immunogen:polymerase(RNA) III(DNA directed) polypeptide K, 12.3 kDa Synonyms:C11, C11 RNP3, hRPC11, HsC11p, My010, POLR3K, RNA polymerase III subunit C10, RNA polymerase III subunit C11, RPC10, RPC11, RPC12.5 Observed MW:12 kDa Uniprot ID:Q9Y2Y1 Reactivity:, Mouse, Rat Tested Application:ELISA, IHC, IF, WB Recommended dilution:WB: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:50-1:500 Gene ID:51728 Research Area:Immunology, Metabolism