ELISA GZMB anti-
Quantity:100µg
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases(aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3,-7,-9 and 10 to give rise to active enzymes mediating apoptosis.
Immunogen:granzyme B
Synonyms:CCPI, CGL 1, CGL1, CSP B, CSPB, CTLA1, CTSGL1, Endogenous granzyme B, Granzyme B, GZMB, HLP, SECT
Observed MW:33 kDa
Uniprot ID:P10144
Reactivity:
Tested Application:ELISA, WB, IHC, IF
Recommended dilution:WB: 1:500-1:2000; IHC: 1:50-1:500; IF: 1:50-1:500
Gene ID:3002
Research Area:Cancer, Immunology, Metabolism