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ELISA GZMB anti-

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Quantity :50µL Clone Number:6A1 Aliases:Granzyme B (EC 3.4.21.79) (C11) (CTLA-1) (Cathepsin G-like 1) (CTSGL1) (Cytotoxic T-lymphocyte proteinase 2) (Lymphocyte protease) (Fragmentin-2) (Granzyme-2) ( lymphocyte protein) (HLP) (SECT) (T-cell serine protease 1-3E), GZMB, CGL1 CSPB CTLA1 GRB Product Type:Recombinant Antibody Immunogen Species:Homo sapiens () UniProt ID:P10144 Immunogen:A syntheQuantityd peptide derived from Granzyme B Raised in: Reactivity: Tested Applications:ELISA, IHC, IF; Recommended dilution: IHC:1:50-1:200, IF:1:20-1:200 Background:This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis. Clonality:Monoclonal Isotype:Rabbit IgG Purification Method:Affinity-chromatography Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:GZMB Research Areas:Cell biology; Immunology

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