ELISA POLB anti-
Quantity :100µL
Clone Number:
Aliases:DNA directed DNA polymerase beta antibody; DNA pol beta antibody; DNA polymerase beta antibody; DNA polymerase beta subunit antibody; DPOLB_ antibody; MGC125976 antibody; Pol B antibody; Pol beta antibody; POLB antibody; Polymerase (DNA directed) beta antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:P06746
Immunogen:SyntheQuantityd peptide derived from DNA Polymerase ?.
Raised in:Rabbit
Reactivity:, Mouse, Rat
Tested Applications:ELISA, WB, IHC; WB:1:500-1:3000, IHC:1:50-1:100
Background:Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sµgar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.
Hiroyuki Matsumoto, Plant Cell Physiol., Nov 1981; 22: 1317 - 1324.
L.K. Karagyozov, Nucleic Acids Res., Jun 1978; 5: 1907 - 1917.
F Costanzo, J. Virol., Mar 1977; 21: 996 - 1001.
AJ Faber, Eur. J. Biochem., Nov 1981; 120: 357.
Clonality:Polyclonal
Isotype:IgG
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conjµgate:Non-conjµgated
Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form:liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:POLB
Research Areas:Epigenetics and Nuclear Signaling
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