ELISA POLB anti-

Quantity :100µL Clone Number: Aliases:DNA directed DNA polymerase beta antibody; DNA pol beta antibody; DNA polymerase beta antibody; DNA polymerase beta subunit antibody; DPOLB_ antibody; MGC125976 antibody; Pol B antibody; Pol beta antibody; POLB antibody; Polymerase (DNA directed) beta antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P06746 Immunogen:SyntheQuantityd peptide derived from DNA Polymerase ?. Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB, IHC; WB:1:500-1:3000, IHC:1:50-1:100 Background:Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sµgar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases. Hiroyuki Matsumoto, Plant Cell Physiol., Nov 1981; 22: 1317 - 1324. L.K. Karagyozov, Nucleic Acids Res., Jun 1978; 5: 1907 - 1917. F Costanzo, J. Virol., Mar 1977; 21: 996 - 1001. AJ Faber, Eur. J. Biochem., Nov 1981; 120: 357. Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:POLB Research Areas:Epigenetics and Nuclear Signaling