ELISA POLH Antibody, FITC
Quantity :50µg
Clone Number:
Aliases:DNA polymerase eta antibody; FLJ16395 antibody; FLJ21978 antibody; Polh antibody; POLH_ antibody; polymerase DNA directed eta antibody; RAD30 antibody; RAD30 homolog A antibody; RAD30A antibody; Xeroderma pigmentosum variant type protein antibody; XP V antibody; XPV antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:Q9Y253
Immunogen:Recombinant DNA polymerase eta protein (408-609AA)
Raised in:Rabbit
Reactivity:
Tested Applications:
Background:DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Plays an important role in the repair of UV-induced pyrimidine dimers. Depending on the context, it inserts the correct base, but causes frequent base transitions and transversions. May play a role in hypermutation at immunoglobµLin genes. Forms a Schiff base with 5\'-deoxyribose phosphate at abasic sites, but does not have lyase activity. Targets POLI to replication foci.
Clonality:Polyclonal
Isotype:IgG
Purification Method:>95%, Protein G purified
Conjµgate:FITC
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:POLH
Research Areas:Epigenetics and Nuclear Signaling
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