ELISA POLH Antibody, FITC

Quantity :50µg Clone Number: Aliases:DNA polymerase eta antibody; FLJ16395 antibody; FLJ21978 antibody; Polh antibody; POLH_ antibody; polymerase DNA directed eta antibody; RAD30 antibody; RAD30 homolog A antibody; RAD30A antibody; Xeroderma pigmentosum variant type protein antibody; XP V antibody; XPV antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9Y253 Immunogen:Recombinant DNA polymerase eta protein (408-609AA) Raised in:Rabbit Reactivity: Tested Applications: Background:DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Plays an important role in the repair of UV-induced pyrimidine dimers. Depending on the context, it inserts the correct base, but causes frequent base transitions and transversions. May play a role in hypermutation at immunoglobµLin genes. Forms a Schiff base with 5\'-deoxyribose phosphate at abasic sites, but does not have lyase activity. Targets POLI to replication foci. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:FITC Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:POLH Research Areas:Epigenetics and Nuclear Signaling