ELISA PLXNB2 anti-

Quantity :50µL Clone Number: Aliases:PLXNB2 antibody; KIAA0315 antibody; Plexin-B2 antibody; MM1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O15031 Immunogen:Recombinant Inhibitor of nuclear factor kappa-B kinase-interacting protein (1458-1673AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB; Recommended dilution: WB:1:500-1:2000 Background:Cell surface receptor for SEMA4C, SEMA4D and SEMA4G that plays an important role in cell-cell signaling. Binding to class 4 semaphorins promotes downstream activation of RHOA and phosphorylation of ERBB2 at \'Tyr-1248\'. Required for normal differentiation and migration of neuronal cells during brain corticogenesis and for normal embryonic brain development. RegµLates the migration of cerebellar granµLe cells in the developing brain. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. May modµLate the activity of RAC1 and CDC42. Down-regµLates macrophage migration in wound-healing assays (in vitro) (By similarity). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Antigen Affinity purified & Affinity purified Conjµgate:Non-conjµgated Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:PLXNB2 Research Areas:Others