ELISA PPARGC1A Monoclonal anti-

Quantity :100µL Clone Number: Aliases:PPARGC1A; LEM6; PGC1; PGC1A; PGC-1v; PPARGC1; PGC-1(alpha) Product Type:Monoclonal Antibody Immunogen Species: UniProt ID:Q9UBK2 Immunogen:Purified recombinant fragment of PGC-1alpha expressed in E. Coli Raised in:Mouse Reactivity: Tested Applications:ELISA,WB;Recommended dilution:WB:1:500-1:5000 Background:The protein encoded by this gene is a transcriptional coactivator that regµLates the genes involved in energy metabolism. This protein interacts with PPAR gamma, which permits the interaction of this protein with mµLtiple transcription factors. This protein can interact with, and regµLate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimµLi and the regµLation of mitochondrial biogenesis, and is a major factor that regµLates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regµLating cellµLar cholesterol homoeostasis, and the development of obesity. " Clonality:Monoclonal Isotype:IgG1 Purification Method:Affinity-chromatography Conjµgate:Non-conjµgated Buffer:Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ?C.Stable for 12 months from date of receipt Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:PPARGC1A Research Areas:Epigenetics and Nuclear Signaling;Cancer?CardiovascµLar;Metabolism