Methods for analyte attachment

Attachment of analyte macromolecules to the crysalin lattice and protocols to array these attached molecules in an identical conformation is essential for the use of crysalins in structure determination.

Covalent attachment of analytes through genetic fusion has been successfully achieved. Alternative approaches include attachment of analyte molecules to a pre-formed lattice via non-covalent interactions.

Methods for analyte attachment

Analyte recruitment options